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Materials and methods Animals and experimental design Nine-week-old male Fischer 344 rats (Charles River Laboratory, Japan), weighing from 180-200 g, were maintained at 23C, given standard laboratory chow and water ad libitum, and kept under a 12 h light (7:00-19:00)/12 h dark schedule

In: Geissler HG, Petzold P, editors

It is now widely accepted that the age-associated reduction in circulating hormones, particularly estrogen, directly accelerates skin aging, a major clinical consequence being delayed repair leading to an increased incidence of chronic wounds

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doi: 10.1016/j.intimp.2023.110924 8 GongSLangSJiangXLiX